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Biomedical applications
Nanomaterials have been investigated as drug delivery agents for decades. However, such systems suffer from long preparation times; high precursor concentrations detrimental to drugs; tedious multistep procedures; and the requirement of custom-synthesised expensive/hazardous precursors.
Green nanomaterials have interesting prospects as carriers of drugs and active biomolecules. A key advantage of using green nanomaterials is that the synthesis is compatible with biological and the materials properties can be tailored.
We are focusing our efforts on:
Nanomaterials have been investigated as drug delivery agents for decades. However, such systems suffer from long preparation times; high precursor concentrations detrimental to drugs; tedious multistep procedures; and the requirement of custom-synthesised expensive/hazardous precursors.
Green nanomaterials have interesting prospects as carriers of drugs and active biomolecules. A key advantage of using green nanomaterials is that the synthesis is compatible with biological and the materials properties can be tailored.
We are focusing our efforts on:
- Green nanomaterials as next generation delivery vehicles.
- Investigating their biocompatibility.
- Utilisation for drug and gene delivery.
- C. R. Steven, G. A. Busby, C. Mather, B. Tariq, M. L. Briuglia, D. A. Lamprou, A. J. Urquhart, M. H. Grant and S. V. Patwardhan. Bioinspired Silica as Drug Delivery Systems and their Biocompatibility Journal of Materials Chemistry B, 2, 5028-5042, 2014. OPEN ACCESS
- Kubiak - Ossowska, K., Burley, G. A., Patwardhan, S. V., and Mulheran, P. A. Spontaneous Membrane-Translocating Peptide Adsorption at Silica Surfaces: A Molecular Dynamics Study Journal of Physical Chemistry B, 117, 14666, 2013.
